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U.S. intelligence underestimated Islamic State activity inside Syria, which has become "ground zero" for jihadists worldwide.
The Nusra Front is facing pressure to reconcile with its rival Islamic State and confront a common enemy after U.S.-led air strikes hit both groups this week.
The President called on more nations to help fight the world's worst outbreak of the deadly virus.
U.S. and coalition planes pounded Islamic State positions again, but the strikes did not halt the fighters' advance in a Kurdish area.